David J. Diller,Axel Metzger,David E. Kaelin, JR.,Steven Paget,Chia-Yu Huang,Brian F. Mcguinness,Audrey Julie Hospital,William Ronald Solvibile, JR.
申请号：
US16662980
公开号：
US20200131209A1
申请日:
2019.10.24
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides compounds of Formula I′；:wherein , W, X, Y, Z, Z1, Z2, R1, R2, R3, R4 and R5 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are effective at modulating the STING protein and thus can be used as medicaments for treating or preventing disorders affected by the agonism of STING.
