A medical article is provided including a chamber formed from a cyclic polyolefin having an inner surface in sliding engagement with an exterior surface of a sealing member, the inner surface of the chamber being coated with a composition including a first mixture of organopolysiloxanes having different molecular weights and a viscosity ranging from about 5,000 centistokes to about 100,000 centistokes and a sealing member having an exterior surface coated with a second mixture of organopolysiloxanes having different molecular weights and having a viscosity ranging from about 10,000 centistokes to about 500,000 centistokes, the coatings being adhered to the surfaces by crosslinking induced by irradiation with an isotope, electron beam, or ultraviolet radiation.