Various embodiments include systems and methods for utilizing depth from ultrasound volume rendering for 3D printing. Volumetric ultrasound dataset may be generated, based on echo ultrasound signals, and one or more volume rendered ultrasound images, based on the volumetric ultrasound dataset, may be displayed. Based on the one or more volume rendered ultrasound images and/or the volumetric ultrasound dataset, three-dimensional (3D) printing data may be generated. The 3D printing data may be configured to enable producing, via a 3D printer, a physical volume representation of one or more objects and/or structures in the one or more volume rendered ultrasound images. The 3D printing data may be based on 3D modeling of at least a portion of at least one of the one or more volume rendered ultrasound images. The 3D modeling may comprise a surface mesh representation.
