Xi Chen,Pingchen Fan,Yandong Li,Jay P. Powers,Viengkham Malathong,Sreenivas Punna,Hiroko Tanaka,Penglie Zhang
申请号：
US15074976
公开号：
US20160303084A1
申请日:
2016.03.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
