WALLIN JEFFREY,PATEL PREMAL,NANNINI MICHELLE,SAMPATH DEEPAK,LIN KUI,PUNNOOSE ELIZABETH
申请号：
NZ61724512
公开号：
NZ617245A
申请日:
2012.03.30
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed herein is a combination comprising a) compound of formula Ia 2-(4-chlorophenyl)-3-(isopropylamino)-1-(4-((R)-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)propan-1-one (GDC-0068/ipatasertib) or a pharmaceutically acceptable salt thereof and 5-FU (fluorouracil) and/or capecitabine. Also disclosed is the use of the combinations for treating hyperproliferative disorders, such as cancer.
