SELS DE DERIVES DE PYRROLOTRIAZINE UTILES EN TANT QU'INHIBITEURS DE TAM

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专利权人:

INCYTE CORPORATION

发明人:

JIA, ZHONGJIANG,WU, YONGZHONG,PAN, YONGCHUN,ZHOU, JIACHENG,LI, QUN

申请号：

CA3077308

公开号：

CA3077308A1

申请日:

2018.09.26

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present application provides salt forms of N-(4-(4-Amino-7-(1- isobutyrylpiperidin-4-yl)pyrrolo[1,2-f][1,2,4]triazin-5-yl)phenyl)-1- isopropyl-2,4-dioxo-3-(pyridin-2-yl)-1,2,3,4-tetrahydropyrimidine-5- carboxamide (I) and N-(4-(4-Amino-7-(1-isobutyrylpiperidin-4-yl) pyrrolo[1,2-f][1,2,4]triazin-5-yl)phenyl)-1-isopropyl-2,4-dioxo-3- phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxamide (II), which are useful as inhibitors of TAM kinases, as well as processes and intermediates related thereto.

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