A luer port alert device and method of alerting a care provider to a condition of a patient therewith prior to administering fluid treatment to the patient is provided. The luer port alert device includes an arcuate body having a through passage extending along a central axis between opposite ends. A bridge member extends from the body over one of the ends generally along the central axis to at least partially obstruct access to the through passage. The bridge member is selectively and resiliently moveable radially outwardly the central axis under an externally applied force to allow full, unobstructed access to the through passage, when desired, and returns to its relaxed position generally along the central axis upon removing the externally applied force.