North Carolina Central University;The University of North Carolina at Chapel Hill
发明人:
Jonathan Z. Sexton,Jay E. Brenman,David L. Musso
申请号：
US16017347
公开号：
US20180370905A1
申请日:
2018.06.25
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.
