compound, pharmaceutical composition, and method of treating a human

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专利权人:

Gilead Calistoga LLC

发明人:

Arthur Yeung,Jennifer A. Treiberg,Jerry Evarts,Lafe J. Pur Purvis,Leena Patel,Musong Kim,Stephane Perreault

申请号：

BR112015014585

公开号：

BR112015014585A2

申请日:

2013.12.20

申请国别(地区):

BR

年份:

2017

代理人:

摘要：

1/1 summary "compound, pharmaceutical composition, and method of treatment of a human" The present disclosure provides phosphatidylinositol 3-kinase (pi3k) inhibitors of the formula (i), 1 or pharmaceutically acceptable salts thereof, wherein r, 2 3 4 5 6 r, n, r, r, r are as defined herein. These compounds are useful for treating conditions mediated by one or more pi3k isoforms, such as pi3k ''. The present disclosure further provides pharmaceutical compositions comprising a compound of formula (i) or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions for treating conditions mediated by one or more pi3k isoforms, such as pi3k ''.1 / 1 resumo “composto, composiã‡ãƒo farmacãšutica, e, mã‰todo de tratamento de um ser humanoâ€� a presente divulgaã§ã£o prov㪠inibidores de fosfatidilinositol 3- quinase (pi3k) da fã³rmula (i), 1 ou sais farmaceuticamente aceitã¡veis da mesma, em que r , 2 3 4 5 6 r , n, r , r , r e r sã£o como aqui definidos. estes compostos sã£o ãºteis para o tratamento de condiã§ãµes mediadas por um ou mais isoformas de pi3k, tal como pi3kî´. a presente divulgaã§ã£o prov㪠adicionalmente composiã§ãµes farmacãªuticas que incluem um composto da fã³rmula (i) ou sais farmaceuticamente aceitã¡veis da mesma, e mã©todos de uso destes compostos e composiã§ãµes para tratar condiã§ãµes mediadas por um ou mais isoformas de pi3k, tal como pi3kî´.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/