CUI XIAOXIA U S A,DAVIS GREGORY U S A,GREGORY PHILIP D U S A,HOLMES MICHAEL C U S A,WEINSTEIN EDWARD J U S A
申请号:
IN3097/KOLNP/2012
公开号:
IN2012KN03097A
申请日:
2012.10.12
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
Disclosed herein are methods and compositions for genome editing of a Rosa locus, using fusion proteins comprising a zinc-finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.