Disclosed is a mixture comprising the compound trans-1,1,1,4,4,4-hexafluoro-2-butene and at least one additional compound selected from the group consisting of HFOs, HFCs, HFEs, CFCs, CO2, olefins, organic acids, alcohols, hydrocarbons, ethers, aldehydes, ketones, and others such as methyl formate, formic acid, trans-1,2 dichloroethylene, carbon dioxide, cis-HFO-1234ze+HFO-1225yez； mixtures of these plus water； mixtures of these plus CO2； mixtures of these trans 1,2-dichloroethylene (DCE)； mixtures of these plus methyl formate； mixtures with cis-HFO-1234ze+CO2； mixtures with cis-HFO-1234ze+HFO-1225yez+CO2； and mixtures with cis-HFO-1234ze+HFC-245fa. Also disclosed are methods of using and products of using the above compositions as blowing agents, solvents, heat transfer compositions, aerosol propellant compositions, fire extinguishing and suppressant compositions.
