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CRISTAL D'UN SEL D'UN COMPOSÉ DE PYRIDINE FUSIONNÉ
专利权人:
ASTELLAS PHARMA INC.
发明人:
KIKUCHI, TAKASHI,GATO, KATSUHIKO,MUKOYOSHI, KOICHIRO,KITAMURA, TSUYOSHI,KAWAKAMI, TAKESHI,YASUDA, HIRONOBU
申请号:
EP11798182
公开号:
EP2592080A4
申请日:
2011.06.22
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
[Problem] A salt or crystal of a compound which is highly stable in a solid state and useful as a bulk material for the preparation of a pharmaceutical product is provided. [Means for Solution] 4-{[(1R,2s,3S,5s,7s)-5-Hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide succinate, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide hydrobromide, and 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide hydrochloride and crystals thereof are useful as a bulk material for the preparation of a solid preparation, in particular, a solid dispersion preparation. Furthermore, the crystal of the hydrobromide has excellent stability in a solid state and is useful as a bulk material for the preparation of a pharmaceutical product.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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