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PRÉPARATION TRANSDERMIQUE DE PEPTIDE ANTIGÉNIQUE ASSOCIÉ AU CANCER
专利权人:
LTD.;SUMITOMO DAINIPPON PHARMA CO.
发明人:
TANAKA, MASAYASU,YAMAMOTO, KAZUMITSU,MAEDA, HIROO,SAITO, KOICHI,SUGINOBE, NATSUKO
申请号:
EP13813675
公开号:
EP2868325A4
申请日:
2013.07.02
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
An object of the present invention is to provide a transdermal preparation showing more efficient induction of CTL by a WT1 protein-derived cancer antigen peptide. The present invention enables more efficient CTL induction by applying a transdermal preparation containing a WT1 protein-derived cancer antigen peptide, and an ether-type additive represented by the formula (1): €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 1 -O-R 2 €ƒ€ƒ€ƒ€ƒ€ƒ(1) [wherein R 1 is a hydrocarbon group having 8 - 24 carbon atoms, and R 2 is a group represented by the formula (2): or a group represented by the formula (3): €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ-(CH 2 CH 2 O) m H€ƒ€ƒ€ƒ€ƒ€ƒ(3) wherein m is an integer of 1 - 18], wherein the additive is liquid at 20°C, to a WT1 protein-derived cancer antigen peptide.
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中国工程科技知识中心
来源网址:
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