KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
发明人:
LEE, Hae Shin,이해신,SHIN, Mi kyung,신미경,LEE, Moon Sue,이문수,KIM, Keumyeon,김금연
申请号：
KRKR2017/010441
公开号：
WO2018/056737A1
申请日:
2017.09.22
申请国别(地区):
WO
年份:
2018
代理人:
摘要：
An injection needle coated with chitosan, in which an oxidized catechol group is introduced into chitosan and crosslinked, according to the present invention, has the ability to immediately suppress bleeding occurring at the time of injection. As such, the present invention is effective for injecting not only patients having low hemostatic ability such as diabetic patients, chemotherapy patients and hemophilia patients, but also for patients showing a blood rejection response and children, and has an effect of immediately suppressing hemorrhage of strong pulsing, blood-rich organs such as a heart.Selon la présente invention, une aiguille dinjection revêtue de chitosane, dans laquelle un groupe catéchol oxydé est introduit dans le chitosane et réticulé, a la capacité de supprimer immédiatement un saignement se produisant au moment de linjection. Ainsi, la présente invention est efficace pour effectuer des injections non seulement sur des patients ayant une faible capacité hémostatique, tels que des patients diabétiques, des patients sous chimiothérapie et des patients hémophiles, mais également sur des patients présentant une réponse de rejet aux transfusions sanguines, ainsi que sur des enfants, et a pour effet de supprimer immédiatement lhémorragie dorganes riches en sang, à fortes pulsations, tels que le coeur.본 발명에 따른 산화된 카테콜기가 키토산에 도입되어 가교된 키토산으로 코팅된 주사바늘은 주사시 발생하는 출혈을 즉각적으로 억제할 수 있어, 당뇨병 환자, 항암치료 환자, 혈우병 환자 등 지혈능력이 떨어지는 환자뿐만 아니라 혈액거부반응을 보이는 환자, 어린이의 주사에도 유용하게 사용할 수 있는 효과가 있으며, 심장과 같은 박동이 강하고 혈액이 많은 장기의 출혈도 즉각적으로 억제할 수 있는 효과가 있다.
