Ivan Lopez-Belmonte Encina,Rafael Ojeda Martinez De Castilla
申请号：
US13122981
公开号：
US08822659B2
申请日:
2009.10.02
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Procedure for the synthesis of deprotected pentasaccharides from a protected precursor pentasaccharide through a reaction procedure having five stages whereamong is included an N-sulphation of amino groups and a hydrogenolysis of benzyl groups. Through this procedure a drastic reduction is achieved in the total synthesis time in comparison with the process traditionally employed, together with increased reproducibility thereof, permitting the standardization thereof.
